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2023
Mechanistic Basis for Red Light Switching of Azonium Ions; Miroslav Medved’, Mariangela Di Donato,Wybren Jan Buma, Adèle D. Laurent, Lucien Lameijer, Tomáš Hrivnák, Ivan Romanov, Susannah Tran, Ben L. Feringa, Wiktor Szymanski* and G. Andrew Woolley* J. Am. Chem. Soc. https://doi.org/10.1021/jacs.3c06157
Engineering of bidirectional, cyanobacteriochrome-based light-inducible dimers (BICYCL)s; Jaewan Jang, Kun Tang, Jeffrey Youn, Sherin McDonald, Hannes M. Beyer, Matias D. Zurbriggen, Maruti Uppalapati & G. Andrew Woolley Nature Methods https://doi.org/10.1038/s41592-023-01764-8
Isomerization of bioactive acylhydrazones triggered by light or thiols; Zhiwei Zhang, Giang N. T. Le, Yang Ge, Xiaowen Tang, Xin Chen, Linda Ejim, Emily Bordeleau, Gerard D. Wright, Darcy C. Burns, Susannah Tran, Peter Axerio-Cilies, Yu Tian Wang, Mingxin Dong & G. Andrew Woolley Nature Chemistry https://www.nature.com/articles/s41557-023-01239-5
2022
Point (S-to-G) Mutations in the W (S/G) GE Motif in Red/Green Cyanobacteriochrome GAF Domains Enhance Thermal Reversion Rates; Jaewan Jang, P. Maximilian M. Reed, Sarah Rauscher, G. Andrew Woolley Biochemistry 61 (14), 1444-1455
Modification of proteins with azobenzene crosslinkers using reversible covalent bonds; Nobuo Yasiuke, Chihiro Kachi-Terajima, Amir Karin, & G. Andrew Woolley Org. Biomol. Chem, 20, 8649-8656
2021
Structure-based design of a photoswitchable affibody scaffold; Ryan M. Woloschuk, P. Maximilian M. Reed, Anna S. I. Jaikaran, Karl Z. Demmans, Jeffrey Youn, Voula Kanelis, Maruti Uppalapati, G. Andrew Woolley Protein Science, 30 (12): 2359-2372 (Journal cover and best paper award)
Directed evolution approaches for optogenetic tool development; Jaewan Jang & G. Andrew Woolley Biochem. Soc. Trans., 49 (6): 2737–2748.
2020
Yeast Two Hybrid Screening of Photo-Switchable Protein–Protein Interaction Libraries; RM Woloschuk, PMM Reed, S McDonald, M Uppalapati, GA Woolley; J. Mol. Biol. 432 (10), 3113-3126
2019
Synthesis and characterization of bis (4-amino-2-bromo-6-methoxy) azobenzene derivatives; D Martínez-López, A Babalhavaeji, D Sampedro, GA Woolley; Beilstein J. Org. Chem. 15 (1), 3000-3008
A time-dependent role for the transcription factor CREB in neuronal allocation to an engram underlying a fear memory revealed using a novel in vivo optogenetic tool to modulate CREB function; A Park, AD Jacob, BJ Walters, S Park, AJ Rashid, JH Jung, J Lau, G. Andrew Woolley, Paul W. Frankland & Sheena A. Josselyn; Neuropsychopharmacology, 1-9, 2019
Photoswitchable Affinity Reagents: Computational Design and Efficient Red‐Light Switching; N Yasuike, KM Blacklock, H Lu, ASI Jaikaran, S McDonald, M Uppalapati, Sagar D Khare, G Andrew Woolley; ChemPhotoChem 3 (6), 431-440, 2019
Detection of Incorporation of p-Coumaric Acid into Photoactive Yellow Protein Variants in Vivo; KE Brechun, D Zhen, A Jaikaran, V Borisenko, M Kumauchi, WD Hoff, Katja M Arndt, G Andrew Woolley; Biochemistry 58 (23), 2682-2694, 2019
A yeast system for discovering optogenetic inhibitors of eukaryotic translation initiation. H Lu, M Mazumder, ASI Jaikaran, A Kumar, EK Leis, X Xu, M Altmann, Alan Cochrane, G Andrew Woolley, ACS Synth. Biol. 8 (4), 744-757, 2019
Selection of Protein–Protein Interactions of Desired Affinities with a Bandpass Circuit; KE Brechun, KM Arndt, GA Woolley, J. Mol. Biol. 431 (2), 391-400, 2019
Green, orange, red, and far-red optogenetic tools derived from cyanobacteriochromes; J Jang, S McDonald, M Uppalapati, A Woolley, bioRxiv, 7694222019
Intramolecular cross-linking of proteins with azobenzene-based cross-linkers N Yasuike, H Lu, P Xia, GA Woolley; Meth. Enzymol. 624, 129-1492019
Illuminating the photoisomerization of a modified azobenzene single crystal by femtosecond absorption spectroscopy; KM Krawczyk, RL Field, LC Liu, M Dong, GA Woolley, RJD Miller, Can. J. Chem. 97 (6), 488-495, 2019.
2018
Discovering selective binders for photoswitchable proteins using phage display; JM Reis, X Xu, S McDonald, RM Woloschuk, ASI Jaikaran, FS Vizeacoumar, GA Woolley, M Uppalapati, ACS Synth. Biol. 7 (10), 2355-2364, 2018
Duplication of a single strand in a β-sheet can produce a new switching function in a photosensory protein; A Kumar, S Nokhrin, RM Woloschuk, GA Woolley, Biochemistry 57 (28), 4093-4104, 2018
Computational design of a photocontrolled cytosine deaminase; KM Blacklock, BJ Yachnin, GA Woolley, SD Khare; J. Am. Chem. Soc. 140 (1), 14-17, 2018
Modular design of optically controlled protein affinity reagents; A Babalhavaeji, GA Woolley; Chem. Comm. 54 (13), 1591-1594, 2018
2017
Near-infrared photoswitching of azobenzenes under physiological conditions; M Dong, A Babalhavaeji, CV Collins, K Jarrah, O Sadovski, Q Dai, GA Woolley, J. Am. Chem. Soc. 139 (38), 13483-13486, 2017
Strategies for the photo-control of endogenous protein activity; KE Brechun, KM Arndt, GA Woolley; Curr. Opin. Struct. Biol. 45, 53-58, 2017
2016
A Red‐Light Azobenzene Di‐Maleimide Photoswitch: Pros and Cons; D Wu, M Dong, CV Collins, A Babalhavaeji, GA Woolley, Advanced Optical Materials 4 (9), 1402-1409, 2016
Molecular Machines; WR Browne, GA Woolley, DH Qu, ChemPhysChem 17 (12), 1713-1714, 2016
Photo control of protein function using photoactive yellow protein; JM Reis, GA Woolley, Optogenetics, 79-92, 2016